Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKCH | P24723 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476795 | 0.75 | CHRM1 (0.45) | HSD17B10KMT2ATDP1MEN1HPGD | |
| SCHEMBL20165468 | 0.75 | USP2 (0.31) | CA1CA2 | |
| SCHEMBL4954192 | 0.71 | MAPT (0.39) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL4955739 | 0.70 | MAPT (0.47) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL14879165 | 0.70 | ALDH1A1 (0.32) | HPGD | |
| SCHEMBL7366685 | 0.69 | CA2 (0.48) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL14375191 | 0.69 | CYP2C9 (0.40) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL30801060 | 0.68 | KDM4A (0.33) | NOS2 | |
| SCHEMBL23845804 | 0.68 | MMP13 (0.36) | CYP2C9KMT2AMEN1 | |
| SCHEMBL9734941 | 0.68 | ACE2 (0.46) | HSD17B10GMNNTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299263-A1 | Hydroxy Alkyl Amines | Elan Pharmaceuticals, Inc. and Pharmacia & Upjohn Company | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299263-A1 | Hydroxy Alkyl Amines | MAOA, PSEN2, PSEN1 | HSD17B10 150/4885GMNN 925/4885TP53 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.