Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691380 | 0.79 | VCAM1 (0.41) | ARALDH1A1CYP2A6KMT2ATSHR | |
| SCHEMBL27098091 | 0.77 | NPC1 (0.38) | CYP2A6KMT2APKMKDM4EMAPT | |
| SCHEMBL27527094 | 0.76 | AR (0.37) | ARTSHR | |
| SCHEMBL28254037 | 0.76 | AR (0.39) | ARALDH1A1CYP2A6KMT2APKM | |
| SCHEMBL14306432 | 0.75 | TUBB4A (0.46) | ALDH1A1CYP2A6KMT2APKMKDM4E | |
| SCHEMBL25257701 | 0.73 | CYP11B2 (0.47) | ARALDH1A1KMT2AKDM4ECYP11B1 | |
| SCHEMBL30510146 | 0.73 | CYP11B2 (0.47) | ARALDH1A1KMT2AKDM4ECYP11B1 | |
| SCHEMBL28320699 | 0.73 | LMNA (0.42) | ALDH1A1KMT2AEGFRERBB2TSHR | |
| SCHEMBL27547023 | 0.72 | AR (0.35) | AR | |
| SCHEMBL14394775 | 0.72 | NPC1 (0.35) | ALDH1A1CYP2A6KMT2APKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854798-A2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | Bristol-Myers Squibb Company (US) | 2007-11-14 | — | — | EP | disclosed |