SCHEMBL25257701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30510146	1.00	CYP11B2 (0.47)	CYP11B2CYP11B1MAOBMAOAAR
	SCHEMBL17827370	0.74	CYP11B2 (0.59)	CYP11B2CYP11B1MAOBMAOAAR
	SCHEMBL14691380	0.73	VCAM1 (0.41)	MAOBMAOAARALDH1A1KDM4E
	SCHEMBL14382142	0.73	AR (0.36)	CYP11B2CYP11B1ARALDH1A1HPGD
	SCHEMBL12496622	0.72	CYP11B2 (0.77)	CYP11B2CYP11B1
	SCHEMBL13440168	0.72	KIF11 (0.47)	CYP11B2CYP11B1AR
	SCHEMBL31663089	0.70	LMNA (0.35)	MAOBMAOAALDH1A1MEN1KMT2A
	SCHEMBL12733363	0.69	CYP11B2 (0.54)	CYP11B2CYP11B1MAOBMAOAAR
	SCHEMBL12496594	0.69	CYP11B1 (0.54)	CYP11B2CYP11B1ARCYP1A2ALDH1A1
	SCHEMBL25299104	0.69	CYP11B2 (0.63)	CYP11B2CYP11B1ARCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.