Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354068 | 0.90 | AGTR1 (0.40) | DAOP2RX4POLBALDH1A1HPGD | |
| SCHEMBL14397606 | 0.71 | ALDH1A1 (0.51) | GAAPOLBALDH1A1HPGD | |
| SCHEMBL1696713 | 0.70 | POLB (0.45) | DAOP2RX4GAALMNAMAPT | |
| SCHEMBL14397205 | 0.68 | ALDH1A1 (0.42) | P2RX4GAALMNAALDH1A1HPGD | |
| SCHEMBL27888984 | 0.68 | LCK (0.48) | DAOP2RX4LCKPRKACACSNK2A2 | |
| SCHEMBL14397212 | 0.68 | ALDH1A1 (0.40) | P2RX4GAALMNAPOLBALDH1A1 | |
| SCHEMBL14396760 | 0.68 | ALDH1A1 (0.47) | PGRGAALMNAPOLBALDH1A1 | |
| SCHEMBL14397210 | 0.67 | GAA (0.45) | GAALMNAMAPTPOLBALDH1A1 | |
| SCHEMBL14396752 | 0.66 | HPGD (0.44) | P2RX4GAALMNAMAPTPOLB | |
| SCHEMBL2915651 | 0.66 | LCK (0.46) | P2RX4LCKPRKACACSNK2A2PRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117289-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-10-18 | — | — | WO | disclosed |