Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170768 | 0.84 | ITGB3 (0.38) | EPHX2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL19766518 | 0.83 | HSD11B1 (0.45) | — | |
| SCHEMBL4569281 | 0.83 | EPHX2 (0.48) | EPHX2EPHX1 | |
| SCHEMBL24170967 | 0.83 | ALDH1A1 (0.40) | EPHX2EPHX1 | |
| SCHEMBL13492942 | 0.81 | EPHX2 (0.54) | EPHX2EPHX1 | |
| SCHEMBL13024410 | 0.81 | EPHX2 (0.54) | EPHX2EPHX1 | |
| SCHEMBL4403505 | 0.79 | EPHX2 (0.47) | EPHX2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL15371153 | 0.78 | TPSAB1 (0.43) | — | |
| SCHEMBL4518519 | 0.77 | GNAI3 (0.51) | EPHX2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL24509167 | 0.77 | EPHX2 (0.50) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279468-B2 | Integrin ligands | ABBOTT GMBH & CO. KG (DE) | 2007-10-09 | — | — | US | disclosed |