SCHEMBL14401432

SCHEMBL14401432

Cc1cccc(Nc2nc(Nc3ccc(Br)cc3)nc(Nc3cccc(CO)c3)n2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 1/20 0.51
PIK3CG P48736 1/20 0.51
KCNH3 Q9ULD8 1/20 0.49
NFKB1 P19838 1/20 0.49
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
SYK P43405 1/20 0.46
GBA1 P04062 2/20 0.46
POLB P06746 2/20 0.45
TP53 P04637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14583172 0.88 PIK3CA (0.52) PIK3CAPIK3CGKCNH3NFKB1MAPT
SCHEMBL4544809 0.88 PIK3CA (0.62) PIK3CAPIK3CGKCNH3NFKB1MAPT
SCHEMBL4568958 0.84 NFKB1 (0.54) KCNH3NFKB1MAPTNPSR1CA12
SCHEMBL14184956 0.83 SYK (0.52) KCNH3NFKB1MAPTNPSR1SYK
SCHEMBL4547556 0.81 KCNH3 (0.54) KCNH3NFKB1MAPTMEN1KMT2A
SCHEMBL17018662 0.79 SYK (0.51) KCNH3NFKB1SYKGBA1POLB
SCHEMBL4547570 0.79 ALDH1A1 (0.50) KCNH3NFKB1MAPTNPSR1MEN1
SCHEMBL20391866 0.78 NFKB1 (0.59) KCNH3NFKB1MAPTNPSR1CA12
SCHEMBL4547557 0.78 KCNH3 (0.53) KCNH3MAPTGBA1POLBTP53
SCHEMBL4544841 0.77 NFKB1 (0.67) KCNH3NFKB1MAPTNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007111387-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed