SCHEMBL4547570

SCHEMBL4547570

COc1ccc(Nc2nc(Nc3ccc(CO)cc3)nc(Nc3cccc(C)c3)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
VSIR Q9H7M9 1/20 0.50
APP P05067 1/20 0.50
MAPT P10636 3/20 0.49
GAA P10253 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KCNH3 Q9ULD8 4/20 0.48
LMNA P02545 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
NFKB1 P19838 2/20 0.48
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
TP53 P04637 2/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544846 0.89 MAPT (0.59) ALDH1A1NPC1RAB9AAPPMAPT
SCHEMBL824521 0.89 MAPT (0.59) ALDH1A1NPC1RAB9AAPPMAPT
SCHEMBL4568958 0.88 NFKB1 (0.54) NPC1RAB9AVSIRAPPMAPT
SCHEMBL4544867 0.87 MAPT (0.56) ALDH1A1NPC1RAB9AAPPMAPT
SCHEMBL4547556 0.85 KCNH3 (0.54) NPC1RAB9AVSIRMAPTMEN1
SCHEMBL14184957 0.85 APP (0.50) ALDH1A1NPC1RAB9AAPPMAPT
SCHEMBL4547558 0.84 KCNH3 (0.55) ALDH1A1NPC1RAB9AVSIRAPP
SCHEMBL14184730 0.83 APP (0.48) ALDH1A1NPC1RAB9AAPPMAPT
SCHEMBL4547557 0.81 KCNH3 (0.53) NPC1RAB9AVSIRMAPTKCNH3
SCHEMBL5462060 0.81 NPSR1 (0.63) ALDH1A1NPC1RAB9AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8395727-B2 VA mode liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-8350999-B2 Liquid-crystal display device having particular retardations and internal hazes FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-20120236235-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236233-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236234-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-8203675-B2 Liquid-crystal display device having retardation films with different optical anisotropy FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-20120120348-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-05-17 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-7990502-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
WO-2007111387-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed