SCHEMBL4547557

SCHEMBL4547557

COc1cccc(Nc2nc(Nc3ccc(C)cc3)nc(Nc3cccc(CO)c3)n2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 2/20 0.53
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
GBA1 P04062 1/20 0.49
VSIR Q9H7M9 1/20 0.49
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
RAB9A P51151 1/20 0.48
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47
TUBA1B P68363 1/20 0.47
TUBA4A P68366 1/20 0.47
TUBB4B P68371 1/20 0.47
TUBB3 Q13509 1/20 0.47
TUBB2A Q13885 1/20 0.47
TUBB8 Q3ZCM7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4547558 0.93 KCNH3 (0.55) KCNH3MAPTGBA1VSIRNPC1
SCHEMBL4547556 0.91 KCNH3 (0.54) KCNH3TP53MAPTGBA1VSIR
SCHEMBL4544832 0.88 KCNH3 (0.65) KCNH3TP53MAPTNPC1POLB
SCHEMBL14184957 0.86 APP (0.50) KCNH3TP53MAPTNPC1RAB9A
SCHEMBL14184956 0.86 SYK (0.52) KCNH3MAPTKDM4EHTTEGFR
SCHEMBL4547449 0.85 EGFR (0.55) KCNH3GBA1VSIRNPC1POLB
SCHEMBL4547555 0.85 KCNH3 (0.50) KCNH3TP53MAPTGBA1VSIR
SCHEMBL4547570 0.81 ALDH1A1 (0.50) KCNH3TP53MAPTVSIRNPC1
SCHEMBL4547448 0.81 SIRT1 (0.49) KCNH3TP53MAPTGBA1VSIR
SCHEMBL4544829 0.80 KCNH3 (0.68) KCNH3MAPTNPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8395727-B2 VA mode liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-20120236235-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236233-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236234-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-8203675-B2 Liquid-crystal display device having retardation films with different optical anisotropy FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-20120120348-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-05-17 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-7990502-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7981488-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
WO-2007111387-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed
WO-2007023990-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORPORATION (JP) 2007-03-01 WO disclosed