Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402960 | 0.94 | THRB (0.35) | TSHRTHRBTHRAALDH1A1KDM4E | |
| SCHEMBL14402565 | 0.93 | THRB (0.37) | TSHRTHRBTHRAHPGDCYP3A4 | |
| SCHEMBL172441 | 0.90 | THRB (0.47) | TSHRTHRBTHRAHPGDTGM2 | |
| SCHEMBL172503 | 0.85 | THRB (0.43) | TSHRTHRBTHRAHPGDTGM2 | |
| SCHEMBL2602471 | 0.84 | SMN1; SMN2 (0.36) | TSHRTHRBALDH1A1HPGDKDM4E | |
| SCHEMBL14402810 | 0.84 | THRB (0.41) | TSHRTHRBTHRAALDH1A1HPGD | |
| SCHEMBL2602527 | 0.81 | ALDH1A1 (0.42) | TSHRTHRBTHRAALDH1A1HPGD | |
| SCHEMBL2602479 | 0.81 | SMN1; SMN2 (0.35) | TSHRTHRBALDH1A1HPGDKDM4E | |
| SCHEMBL14402755 | 0.81 | ELANE (0.37) | THRBATMHSD17B10GAALMNA | |
| SCHEMBL14402958 | 0.81 | ELANE (0.37) | THRBATMHSD17B10GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847881-A2 | Image forming apparatus, image forming method, and process cartridge | Ricoh Company, Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |