Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650151 | 0.81 | ALDH1A1 (0.38) | ALDH1A1ATML3MBTL1 | |
| SCHEMBL16829654 | 0.81 | ALDH1A1 (0.34) | ALDH1A1ATML3MBTL1 | |
| SCHEMBL14406677 | 0.81 | BRD4 (0.43) | ALDH1A1ATMGPR119 | |
| SCHEMBL309779 | 0.79 | GPR119 (0.56) | GPR119 | |
| SCHEMBL3504427 | 0.79 | ALDH1A1 (0.31) | ALDH1A1ATM | |
| SCHEMBL458216 | 0.78 | GPR119 (0.38) | ALDH1A1ATMGPR119 | |
| SCHEMBL12016032 | 0.77 | GNAI3 (0.45) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL155583 | 0.77 | EPHX2 (0.41) | ALDH1A1L3MBTL1GNAI3GNAO1GNAI1 | |
| SCHEMBL4438764 | 0.76 | GPR119 (0.44) | ALDH1A1ATMGPR119ITGB3ITGA2B | |
| SCHEMBL3132682 | 0.76 | RAB9A (0.42) | L3MBTL1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
| US-20220315556-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-10-06 | — | — | US | disclosed |
| EP-3790871-A1 | FURIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |
| CN-103755686-B | The piperidyl with platelet aggregation inhibitory activity replaces 5-hydroxyryptophan derivative | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-103755686-A | Piperidyl substituted 5-hydroxytryptophane derivatives with anti-platelet aggregation activity | UNIV CHINA PHARMA | 2014-04-30 | — | — | CN | disclosed |
| CN-101932580-B | Imidazopyridine kinase inhibitors | GLAXOSMITHKLINE LLC | 2013-05-22 | — | — | CN | disclosed |
| EP-2162454-B1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| CN-101932580-A | Imidazopyridine kinase inhibitors | GLAXOSMITHKLINE LLC | 2010-12-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315556-A1 | FURIN INHIBITORS | FURIN, TGFB1, PCSK7 | ALDH1A1 3733/4885ATM 3778/4885L3MBTL1 3062/4885 |
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | ALDH1A1 3733/4885ATM 3778/4885L3MBTL1 3062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.