Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.47 |
| ▸ | NME4 | O00746 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | GCDH | Q92947 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717434 | 0.86 | MAPK1 (0.71) | CA1CA2MAPK1SIRT5NME4 | |
| SCHEMBL3211210 | 0.79 | CA1 (0.63) | CA1CA2MAPK1SIRT5NME4 | |
| Betamipron SCHEMBL605899 | 0.78 | PRSS1 (0.70) | CA1CA2MAPK1PRSS1CTSG | |
| Betamipron SCHEMBL4498475 | 0.78 | PRSS1 (0.70) | CA1CA2MAPK1PRSS1CTSG | |
| SCHEMBL10340463 | 0.78 | KDM4E (0.54) | CA1CA2MAPK1KDM4EMAPT | |
| SCHEMBL8879067 | 0.77 | CA1 (0.61) | CA1CA2MAPK1SIRT5NME4 | |
| SCHEMBL279993 | 0.77 | LMNA (0.71) | CA1CA2MAPK1CYP1A2CYP2C9 | |
| SCHEMBL1520329 | 0.77 | NPC1 (0.63) | CA1CA2MAPK1SIRT5EPHX2 | |
| SCHEMBL5625471 | 0.77 | CYP1A2 (0.66) | CA1CA2MAPK1CYP1A2CYP2C19 | |
| SCHEMBL17946072 | 0.77 | CA1 (0.61) | CA1CA2MAPK1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271253-B1 | Safe process for the preparation of balsalazide | APOTEX PHARMACHEM INC. (CA) | 2007-09-18 | — | — | US | disclosed |