Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107537 | 0.79 | KDM4E (0.80) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL14408232 | 0.78 | CA1 (0.56) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL240289 | 0.76 | TSHR (0.50) | CA1CA2CA9SMN1; SMN2NPC1 | |
| SCHEMBL30450105 | 0.74 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL1742166 | 0.74 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL24224263 | 0.74 | KDM4E (0.71) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL71847 | 0.73 | KDM4E (0.65) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL10340337 | 0.73 | MMP1 (0.59) | KDM4EALDH1A1 | |
| SCHEMBL936016 | 0.72 | HIF1A (0.69) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL22030672 | 0.72 | GAA (0.68) | KDM4EMAPTHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158507-B1 | REAGENT COMPOSITION, DRY ELEMENT AND METHOD FOR DETERMINATION OF TOTAL BILIRUBIN | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0158507-A2 | Reagent composition, dry element and method for determination of total bilirubin | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-10-16 | — | — | EP | claimed |
| EP-0158507-B1 | REAGENT COMPOSITION, DRY ELEMENT AND METHOD FOR DETERMINATION OF TOTAL BILIRUBIN | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0158506-B1 | METHOD AND APPARATUS FOR DETERMINATION OF AN ANALYTE AND METHOD OF CALIBRATING SUCH APPARATUS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4627014-A | Chemical analyzer for the determination of an analyte | EASTMAN KODAK COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| EP-0087599-B1 | DIAZONIUM SALTS AND REAGENTS FOR BILIRUBIN ASSAY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4548905-A | Reagent composition, dry element and method for determination of total bilirubin | EASTMAN KODAK COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0158507-A2 | Reagent composition, dry element and method for determination of total bilirubin | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0158506-A2 | Method and apparatus for determination of an analyte and method of calibrating such apparatus | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4468467-A | Diazonium salt for bilirubin assay | EASTMAN KODAK COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0087599-A1 | Diazonium salts and reagents for bilirubin assay | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-09-07 | — | — | EP | disclosed |