Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394145 | 1.00 | MAPT (0.34) | MAPTRAB9AL3MBTL1ALDH1A1CHRNB2 | |
| SCHEMBL5394151 | 1.00 | MAPT (0.34) | MAPTRAB9AL3MBTL1ALDH1A1CHRNB2 | |
| SCHEMBL14408909 | 0.86 | L3MBTL1 (0.36) | MAPTRAB9AL3MBTL1ALDH1A1CHRNB2 | |
| SCHEMBL14408910 | 0.86 | ALDH1A1 (0.33) | MAPTRAB9AL3MBTL1ALDH1A1CHRNB2 | |
| SCHEMBL7657443 | 0.84 | CHRNB2 (0.38) | MAPTALDH1A1CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL7657366 | 0.81 | CHRNB2 (0.36) | MAPTALDH1A1CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL10028752 | 0.78 | ALDH1A1 (0.41) | MAPTRAB9AL3MBTL1ALDH1A1CHRNB2 | |
| SCHEMBL7671788 | 0.77 | CHRNB2 (0.39) | MAPTALDH1A1CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL7754488 | 0.77 | CHRNB2 (0.39) | MAPTALDH1A1CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL7672435 | 0.75 | CHRNB2 (0.41) | MAPTALDH1A1CHRNB2CHRNA4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271184-B2 | Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides | NOVARTIS ANIMAL HEALTH US, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-7271184-B2 | Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides | NOVARTIS ANIMAL HEALTH US, INC. (US) | 2007-09-18 | — | — | US | disclosed |