Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.45 |
| ▸ | WHR1 | P49842 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 5/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256741 | 0.92 | WHR1 (0.45) | PDE5AWHR1EHMT2KDM1AAPP | |
| SCHEMBL14256444 | 0.86 | MERTK (0.53) | PDE5AWHR1APPBCHEACHE | |
| SCHEMBL14256699 | 0.85 | MERTK (0.52) | PDE5AAPPBCHEACHEMERTK | |
| SCHEMBL14256734 | 0.84 | EHMT2 (0.47) | PDE5AWHR1EHMT2KDM1AAPP | |
| SCHEMBL14412248 | 0.84 | APP (0.45) | WHR1EHMT2KDM1AAPPBCHE | |
| SCHEMBL14256700 | 0.83 | APP (0.46) | WHR1EHMT2KDM1AAPPBCHE | |
| SCHEMBL14412272 | 0.83 | CXCR4 (0.52) | WHR1APPBCHEACHEMERTK | |
| SCHEMBL14412234 | 0.83 | GBA1 (0.49) | APPBCHEACHEMERTKLMNA | |
| SCHEMBL14412273 | 0.81 | EHMT2 (0.44) | WHR1EHMT2KDM1AAPPBCHE | |
| SCHEMBL14256736 | 0.81 | DNMT3A (0.53) | WHR1EHMT2KDM1AACHEMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213319-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213319-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213319-A1 | Modulators of hepatocyte growth factor/c-Met activity | HGF, MET, HDGF | PDE5A 2957/4885WHR1 2846/4885EHMT2 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.