Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.74 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | ATIC | P31939 | 2/20 | 0.49 |
| ▸ | MPL | P40238 | 4/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12960419 | 0.80 | CYP1A2 (0.82) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL14580408 | 0.79 | CYP1A2 (0.60) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL6654290 | 0.78 | CTRB1 (0.82) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL7764792 | 0.77 | MPL (0.70) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL28551711 | 0.76 | CYP1A2 (0.70) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL25926116 | 0.76 | CYP1A2 (0.70) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL15115349 | 0.76 | CYP1A2 (0.70) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| E122 SCHEMBL110093 | 0.75 | CYP1A2 (0.78) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| E122 SCHEMBL345295 | 0.75 | CYP1A2 (0.78) | CYP1A2CTRB1MEN1KMT2ANSD2 | |
| SCHEMBL29378273 | 0.75 | CYP1A2 (0.68) | CYP1A2CTRB1MEN1KMT2ANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264932-B2 | Nuclease inhibitor cocktail | APPLERA CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | AMBION, INC (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | RNASE1, RNASEH1, RNASEL | CYP1A2 4375/4885CTRB1 141/4885MEN1 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.