Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737575 | 0.90 | HDAC1 (0.69) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8278956 | 0.89 | MTNR1A (0.59) | HDAC1HDAC2MAPTL3MBTL1NPC1 | |
| SCHEMBL7738398 | 0.88 | HDAC1 (0.72) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7739114 | 0.88 | HDAC1 (0.72) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7049002 | 0.85 | MMP2 (0.70) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL21993319 | 0.83 | MMP3 (0.67) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL21993318 | 0.82 | MMP3 (0.66) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7733929 | 0.81 | MAPT (0.66) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9877712 | 0.81 | LTA4H (0.60) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL16380448 | 0.81 | MMP2 (0.74) | MMP3HDAC1HDAC2MAPTMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070205395-A1 | Liquid crystalline polyrotaxane | THE UNIVERSITY OF TOKYO (JP) | 2007-09-06 | — | — | US | disclosed |