Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 7/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418776 | 0.85 | KMT2A (0.42) | ALDH1A1NPC1RAB9ATSHRMEN1 | |
| SCHEMBL14418772 | 0.84 | KISS1R (0.44) | ALDH1A1NPC1RAB9ATSHRMEN1 | |
| SCHEMBL14613336 | 0.84 | KDM4E (0.46) | ALDH1A1NPC1RAB9ATSHRMEN1 | |
| SCHEMBL14418845 | 0.83 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL13120219 | 0.80 | CDK2 (0.58) | ALDH1A1NPC1RAB9ATSHRMEN1 | |
| SCHEMBL12954520 | 0.79 | GSK3B (0.43) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL14050826 | 0.79 | EPHX1 (0.46) | ALDH1A1NPC1RAB9ATSHRMEN1 | |
| SCHEMBL14043195 | 0.79 | NTRK1 (0.41) | ALDH1A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL14418659 | 0.78 | MAPT (0.40) | ALDH1A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL14607070 | 0.78 | DRD2 (0.43) | ALDH1A1NPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225270-A1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225270-A1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | CDK2, CDKN1A, CDK1 | ALDH1A1 2518/4885NPC1 4113/4885RAB9A 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.