Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607070 | 0.95 | DRD2 (0.43) | ALDH1A1MAPTMAPK1SLC16A3SMN1; SMN2 | |
| SCHEMBL14043195 | 0.84 | NTRK1 (0.41) | ALDH1A1MAPTMAPK1AHRSMN1; SMN2 | |
| SCHEMBL14545972 | 0.84 | GSK3B (0.46) | ALDH1A1MAPTMAPK1SMN1; SMN2CDK2 | |
| SCHEMBL14581637 | 0.84 | CDK2 (0.49) | CCNE1CDK2GSK3B | |
| SCHEMBL14418855 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14043329 | 0.81 | KISS1R (0.38) | CCNE1CDK2IKBKBKISS1RGSK3B | |
| SCHEMBL14418776 | 0.81 | KMT2A (0.42) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13288754 | 0.80 | CDK2 (0.45) | MAPTSLC16A3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13120304 | 0.80 | CDK2 (0.58) | CCNE1CDK2GSK3B | |
| SCHEMBL12954520 | 0.79 | GSK3B (0.43) | MAPTSMN1; SMN2NPC1RAB9ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225270-A1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225270-A1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | CDK2, CDKN1A, CDK1 | ALDH1A1 2518/4885MAPT 3326/4885MAPK1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.