Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832781 | 0.86 | MAPT (0.44) | KMT2AMAPTGAAALDH1A1TP53 | |
| SCHEMBL28340396 | 0.83 | KMT2A (0.37) | KMT2AMAPTGAAALDH1A1TP53 | |
| SCHEMBL15484309 | 0.81 | MAPT (0.58) | KMT2AMAPTGAAALDH1A1RAPGEF4 | |
| SCHEMBL18550697 | 0.78 | L3MBTL1 (0.40) | KMT2AMAPTGAAALDH1A1RAPGEF4 | |
| SCHEMBL1192648 | 0.78 | GAA (0.67) | KMT2AMAPTGAAALDH1A1TP53 | |
| SCHEMBL457132 | 0.78 | MAPT (0.77) | KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL20560235 | 0.77 | MAPT (0.46) | KMT2AMAPTGAAALDH1A1RAPGEF4 | |
| SCHEMBL1885075 | 0.77 | KMT2A (0.48) | KMT2AMAPTGAAALDH1A1TP53 | |
| SCHEMBL11883304 | 0.77 | KMT2A (0.42) | KMT2AMAPTGAAALDH1A1RAPGEF4 | |
| SCHEMBL5154372 | 0.77 | ALDH1A1 (0.48) | KMT2AMAPTALDH1A1RAPGEF4FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129765-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | DAICEL CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| EP-4108705-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | Daicel Corporation (JP) | 2022-12-28 | — | — | EP | disclosed |
| CN-115135697-A | Process for producing polythioether compound | 株式会社大赛璐 | 2022-09-30 | — | — | CN | disclosed |
| CN-113278149-A | Process for producing polythioether compound | 株式会社大赛璐 | 2021-08-20 | — | — | CN | disclosed |
| EP-2700636-B1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | ASAHI CHEMICAL IND (JP) | 2017-08-02 | — | — | EP | disclosed |
| CN-103717593-B | Regulate kinase whose compositions and method | 克勒韦谢尔制药公司 | 2016-07-06 | — | — | CN | disclosed |
| US-9359324-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| CN-103476764-B | Process for producing episulfide compound | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2016-05-25 | — | — | CN | disclosed |
| EP-2718290-B1 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE | CLEVEXEL PHARMA (FR) | 2016-05-04 | — | — | EP | disclosed |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-16 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-04-17 | — | — | US | disclosed |
| EP-2700636-A1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | Asahi Kasei Chemicals Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| CN-103476764-A | Process for producing episulfide compound | ASAHI KASEI CHEMICALS CORP (JP) | 2013-12-25 | — | — | CN | disclosed |
| WO-2012172438-A9 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE | DYNAMIX PHARMACEUTICALS LTD. (IL) | 2013-02-07 | — | — | WO | disclosed |
| WO-2012172438-A2 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE | DYNAMIX PHARMACEUTICALS LTD. (IL) | 2012-12-20 | — | — | WO | disclosed |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | KMT2A 867/4885MAPT 4698/4885GAA 4338/4885 |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | KMT2A 792/4885MAPT 680/4885GAA 266/4885 |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | KMT2A 3041/4885MAPT 2242/4885GAA 2311/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | KMT2A 2961/4885MAPT 2173/4885GAA 1748/4885 |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | KMT2A 867/4885MAPT 4698/4885GAA 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.