Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12415073 | 0.88 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR2KMT2AMEN1 | |
| SCHEMBL12922916 | 0.81 | HSD17B1 (0.41) | HSD17B1HSD17B2ESR2LMNAHTT | |
| SCHEMBL12922960 | 0.81 | KDM4E (0.45) | HSD17B1HSD17B2ESR2LMNAESR1 | |
| SCHEMBL12415075 | 0.81 | KDM4E (0.45) | HSD17B1HSD17B2ESR2LMNAESR1 | |
| SCHEMBL14421091 | 0.81 | LMNA (0.38) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL12005179 | 0.76 | CYP3A4 (0.41) | HSD17B1HSD17B2ESR2KMT2AMEN1 | |
| SCHEMBL15424790 | 0.76 | HTT (0.38) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL278561 | 0.76 | CYP2D6 (0.50) | ESR2LMNAHTTESR1MAPT | |
| SCHEMBL14639867 | 0.73 | CYP3A4 (0.38) | HSD17B1HSD17B2LMNAHTTKMT2A | |
| SCHEMBL9464262 | 0.72 | MAPT (0.48) | ESR2LMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830228-B1 | COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2015-08-05 | — | — | EP | disclosed |
| EP-1830228-A1 | COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-09-05 | — | — | EP | disclosed |