Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.65 |
| ▸ | RXRA | P19793 | 11/20 | 0.47 |
| ▸ | RXRB | P28702 | 8/20 | 0.47 |
| ▸ | RARB | P10826 | 13/20 | 0.46 |
| ▸ | RARG | P13631 | 12/20 | 0.46 |
| ▸ | RXRG | P48443 | 6/20 | 0.46 |
| ▸ | RARA | P10276 | 11/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084734 | 0.84 | CYP26B1 (0.75) | CYP26B1RXRARXRBRARBRARG | |
| SCHEMBL14425234 | 0.82 | CYP26B1 (0.59) | CYP26B1RXRARXRBRARBRARG | |
| SCHEMBL22838105 | 0.79 | CYP26B1 (1.00) | CYP26B1RXRARXRBRARBRARG | |
| SCHEMBL29806443 | 0.79 | RARA (0.72) | CYP26B1RXRARXRBRARBRARG | |
| SCHEMBL1132946 | 0.79 | RARA (0.72) | CYP26B1RXRARXRBRARBRARG | |
| SCHEMBL8459952 | 0.76 | RXRA (0.66) | CYP26B1RXRARXRBRARBRARG | |
| SCHEMBL501852 | 0.76 | CYP26B1 (0.57) | CYP26B1RXRARARBRARGRARA | |
| SCHEMBL501853 | 0.76 | CYP26B1 (0.57) | CYP26B1RXRARARBRARGRARA | |
| SCHEMBL501581 | 0.74 | RARB (0.60) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL14425203 | 0.74 | RARB (0.60) | RXRARXRBRARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |