Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fosfomycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfomycin SCHEMBL9634052 | 1.00 | LMNA (0.48) | — | |
| Fosfomycin SCHEMBL788599 | 1.00 | LMNA (0.48) | — | |
| Fosfomycin SCHEMBL3168929 | 0.97 | — | — | |
| Fosfomycin SCHEMBL8633252 | 0.97 | — | — | |
| Fosfomycin SCHEMBL3168937 | 0.97 | — | — | |
| Fosfomycin SCHEMBL9634477 | 0.97 | — | — | |
| Fosfomycin SCHEMBL10492648 | 0.97 | — | — | |
| Fosfomycin SCHEMBL989825 | 0.97 | — | — | |
| Fosfomycin SCHEMBL5595663 | 0.97 | LMNA (0.50) | — | |
| Fosfomycin SCHEMBL50951 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119950812-A | Bacterial response type static direct-writing composite patch and preparation method thereof | 东华大学 | 2025-05-09 | — | — | CN | claimed |
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-113916927-B | Method for measuring related substances in fosfomycin sodium by utilizing nuclear magnetic resonance hydrogen spectrum | 易克斯有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119177162-A | Staphylococcus aureus test piece and application thereof | 北京纳百生物科技有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-119178814-A | Method and kit for detecting content of fosfomycin sodium for injection by using high performance liquid chromatography | 广州艾奇西医药科技有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-222012551-U | Drying device for fosfomycin sodium salt | 开元制药(安徽)有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-112739307-B | Infusion system | 吴制药有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118319850-B | Injection of fosfomycin sodium and preparation method thereof | 山东康美乐医药科技有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118006561-B | High-cracking-rate campylobacter jejuni bacteriophage RDP-CJ-22002, and bactericidal composition and application thereof | 瑞科盟(青岛)生物工程有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-100392395-C | A method for preparing stationary phase of liquid chromatogram of modified zirconia or its composite oxides | UNIV WUHAN (CN) | 2008-06-04 | — | — | CN | claimed |
| CN-1268628-C | New method for preparing neutral sodium fosfomycin | DONGBEI PHARMACY MAIN PLANT (CN) | 2006-08-09 | — | — | CN | claimed |
| CN-1264852-C | Novel pulveres fosfomycin trometamol synthetic method | NORTHEAST GENERAL PHARMACEUTIC (CN) | 2006-07-19 | — | — | CN | claimed |
| CN-1731173-A | A method for preparing stationary phase of liquid chromatogram of modified zirconia or its composite oxides | UNIV WUHAN (CN) | 2006-02-08 | — | — | CN | claimed |
| US-20050025807-A1 | Cured porous calcium phosphate material and uses thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY | 2005-02-03 | — | — | US | claimed |
| CN-1544440-A | Novel pulveres fosfomycin trometamol synthetic method | 东北制药总厂 | 2004-11-10 | — | — | CN | claimed |
| CN-1539842-A | New method for preparing neutral sodium fosfomycin | 东北制药总厂 | 2004-10-27 | — | — | CN | claimed |
| US-5314881-A | Wound healing | Rapisarda, Nunzio (IT) | 1994-05-24 | — | — | US | claimed |
| EP-0213704-A2 | Mixtures of mono- and disodium salts of fosfomycin | COMPANIA ESPANOLA DE LA PENICILINA Y ANTIBIOTICOS, S.A. (ES) | 1987-03-11 | — | — | EP | claimed |
| US-4607024-A | Epoxypropylphosphonate salt of jesamycin and pharmaceutical composition containing same | SCHERING S.P.A. (IT) | 1986-08-19 | — | — | US | claimed |