Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449276 | 1.00 | CTSS (0.51) | CTSSIRAK4P2RX7SOS2NOTUM | |
| SCHEMBL17200145 | 0.85 | IRAK4 (0.43) | CTSSIRAK4P2RX7CTSKSYK | |
| SCHEMBL24794162 | 0.84 | CTSS (0.49) | CTSSIRAK4SOS2CTSKIDH1 | |
| SCHEMBL2960222 | 0.79 | CTSK (0.41) | CTSSIRAK4SOS2CTSKIDH1 | |
| SCHEMBL2514328 | 0.79 | P2RX7 (0.43) | CTSSIRAK4P2RX7NOTUMIDH1 | |
| SCHEMBL30627137 | 0.79 | P2RX7 (0.40) | CTSSIRAK4P2RX7NOTUMIDH1 | |
| SCHEMBL19873380 | 0.79 | P2RX7 (0.40) | CTSSIRAK4P2RX7NOTUMIDH1 | |
| SCHEMBL25305047 | 0.78 | CTSS (0.41) | CTSSIRAK4P2RX7SOS2CTSK | |
| SCHEMBL995983 | 0.77 | SOS2 (0.50) | CTSSSOS2CTSKIDH1 | |
| SCHEMBL3295150 | 0.77 | P2RX7 (0.50) | P2RX7NOTUMIDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103874685-B | Process for the preparation of 4-amino-3-chloro-5-fluoro-6- (substituted) pyridine-2-carboxylic acid esters | DOW AGROSCIENCES LLC (US) | 2016-02-03 | — | — | CN | claimed |
| CN-103458689-B | The preparation method of 4-amino-5-fluorine-3-halo-6-(replacement) pyridine-2-manthanoate | DOW AGROSCIENCES LLC (US) | 2015-09-23 | — | — | CN | claimed |
| CN-103429082-B | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC | 2015-05-06 | — | — | CN | claimed |
| CN-103458689-A | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES LLC | 2013-12-18 | — | — | CN | claimed |
| CN-103429082-A | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC | 2013-12-04 | — | — | CN | claimed |
| US-12433895-B2 | Therapeutically active compounds and their methods of use | SERVIER PHARMACEUTICALS LLC (US) | 2025-10-07 | — | — | US | disclosed |
| US-20240335448-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | PHARMARESROUCES (SHANGHAI) CO., LTD. (CN) | 2024-10-10 | — | — | US | disclosed |
| WO-2024126619-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE | NOVALED GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024126528-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE | NOVALED GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024046607-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE | NOVALED GMBH (DE) | 2024-03-07 | — | — | WO | disclosed |
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11844758-B2 | Therapeutically active compounds and their methods of use | SERVIER PHARMACEUTICALS LLC (US) | 2023-12-19 | — | — | US | disclosed |
| EP-1246802-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-03-14 | — | — | EP | disclosed |
| CN-1281591-C | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | CN | disclosed |
| EP-1498413-A1 | 4-Aminopicolinates and their use as herbicides | Dow AgroSciences LLC (US) | 2005-01-19 | — | — | EP | disclosed |
| CN-1416419-A | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2003-05-07 | — | — | CN | disclosed |
| EP-1246802-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2002-10-09 | — | — | EP | disclosed |
| US-20010047099-A1 | 4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2001-11-29 | — | — | US | disclosed |
| US-6297197-B1 | DEMONSTRATING A BROAD SPECTRUM OF WEED CONTROL. | DOW AGROSCIENCES LLC | 2001-10-02 | — | — | US | disclosed |
| WO-2001051468-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12433895-B2 | Therapeutically active compounds and their methods of use | MCL1, TP53, BRDT | CTSS 115/4885IRAK4 2978/4885P2RX7 3486/4885 |
| US-11844758-B2 | Therapeutically active compounds and their methods of use | MCL1, TP53, BRDT | CTSS 115/4885IRAK4 2978/4885P2RX7 3486/4885 |
| US-20240335448-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | MCL1, TP53, BRDT | CTSS 115/4885IRAK4 2978/4885P2RX7 3486/4885 |
| US-20010047099-A1 | 4-aminopicolinates and their use as herbicides | AADAT, ABAT, DDT | CTSS 3363/4885IRAK4 3446/4885P2RX7 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.