Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753696 | 0.90 | HTR2A (0.61) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL7005718 | 0.84 | HTR2A (0.71) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL7004146 | 0.84 | HTR2A (0.71) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL7004071 | 0.82 | HTR2A (0.69) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL7889427 | 0.82 | HTR2A (0.69) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL7001306 | 0.82 | HTR2A (0.69) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL266641 | 0.81 | SLC6A4 (0.68) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL14161475 | 0.80 | HTR2A (0.57) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL21846455 | 0.80 | SLC6A4 (0.51) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C | |
| SCHEMBL4985934 | 0.80 | HTR2A (0.77) | SLC6A4HTR2ACYP3A4CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833122-B2 | Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases | CALGENT BIOTECHNOLOGY CO., LTD. (TW) | 2023-12-05 | — | — | US | disclosed |
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | CCKAR, CCKBR, GRPR | SLC6A4 1104/4885HTR2A 339/4885CYP3A4 1582/4885 |
| US-11833122-B2 | Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases | KEAP1, GOT2, COL1A1 | SLC6A4 4330/4885HTR2A 4186/4885CYP3A4 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.