Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430362 | 0.88 | PTGS2 (0.43) | PTGS2ALDH1A1TSHRPKMKDM4E | |
| SCHEMBL14430349 | 0.87 | LMNA (0.48) | PTGS2ALDH1A1TSHRPKMKDM4E | |
| SCHEMBL14441289 | 0.84 | MEN1 (0.51) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL2612522 | 0.81 | PTGS2 (0.70) | PTGS2ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL17933018 | 0.80 | HTT (0.49) | KDM4EMEN1KMT2ARECQLLMNA | |
| SCHEMBL17935888 | 0.80 | ADRB2 (0.52) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL6261834 | 0.79 | PTGS2 (0.49) | PTGS2ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL374405 | 0.78 | KDM4E (0.54) | PTGS2ALDH1A1TSHRPKMKDM4E | |
| SCHEMBL19608786 | 0.78 | PTGS2 (0.57) | PTGS2ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL14430339 | 0.78 | HTT (0.59) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-20070190151-A1 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2007-08-16 | — | — | US | disclosed |
| US-20070190151-A1 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190151-A1 | Method of preparing dendritic drugs | MYD88, TLR3, TLR6 | PTGS2 1564/4885ALDH1A1 3848/4885TSHR 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.