Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539124 | 0.91 | ALDH1A1 (0.55) | PTGS2LMNATSHRTP53CYP3A4 | |
| SCHEMBL17498842 | 0.86 | PTGS2 (0.59) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL11327527 | 0.81 | PTGS2 (0.71) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL12715080 | 0.81 | PTGS2 (0.75) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL9446603 | 0.81 | PTGS2 (0.75) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL2612522 | 0.80 | PTGS2 (0.70) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL11985699 | 0.80 | PTGS2 (0.72) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL14430409 | 0.78 | PTGS2 (0.48) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL6261834 | 0.78 | PTGS2 (0.49) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL6550292 | 0.78 | PTGS2 (0.67) | PTGS2KDM4EHSD17B10LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211664-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2022-07-07 | — | — | US | disclosed |
| US-11311512-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2022-04-26 | — | — | US | disclosed |
| US-20190105299-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2019-04-11 | — | — | US | disclosed |
| US-20170326103-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220211664-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | PTGS2 1000/4885KDM4E 3054/4885HSD17B10 1871/4885 |
| US-11311512-B2 | Lymph directing prodrugs | LTA, ABCB11, LYN | PTGS2 1000/4885KDM4E 3054/4885HSD17B10 1871/4885 |
| US-20190105299-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | PTGS2 1000/4885KDM4E 3054/4885HSD17B10 1871/4885 |
| US-20170326103-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | PTGS2 1000/4885KDM4E 3054/4885HSD17B10 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.