Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439972 | 0.93 | SLC6A9 (0.51) | SLC6A9MAPTEGLN1TRPC3NOTUM | |
| SCHEMBL1440776 | 0.84 | MAPT (0.55) | SLC6A9MAPTTRPC3LMNATP53 | |
| SCHEMBL1440170 | 0.84 | MAPT (0.55) | SLC6A9MAPTTRPC3LMNATP53 | |
| SCHEMBL1440054 | 0.81 | PTGES (0.52) | MAPTLMNATP53HPGDTSHR | |
| SCHEMBL1440421 | 0.79 | PTGES (0.52) | MAPTLMNATP53TSHR | |
| SCHEMBL1443417 | 0.78 | TP53 (0.44) | SLC6A9MAPTEGLN1TRPC3LMNA | |
| SCHEMBL1439951 | 0.78 | MAPT (0.52) | MAPTEGLN1TRPC3LMNANPY5R | |
| SCHEMBL1441243 | 0.78 | MAPT (0.52) | MAPTLMNATP53 | |
| SCHEMBL1440520 | 0.78 | GAA (0.55) | MAPTLMNATP53 | |
| SCHEMBL1440521 | 0.76 | MAPT (0.55) | MAPTLMNATP53NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023812-A1 | MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 (MPGES1) INHIBITORS | NOVASAID AB (SE) | 2011-03-03 | — | — | WO | disclosed |