Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1440561 | 0.90 | TP53 (0.50) | GAATP53LMNAMAPTPOLB | |
| SCHEMBL1440413 | 0.83 | TP53 (0.60) | TP53LMNAMAPTPOLB | |
| SCHEMBL1440054 | 0.83 | PTGES (0.52) | TP53LMNAMAPTPTGES | |
| SCHEMBL1440237 | 0.82 | TP53 (0.64) | TP53LMNAMAPTPOLB | |
| SCHEMBL1440421 | 0.81 | PTGES (0.52) | TP53LMNAMAPTPTGES | |
| SCHEMBL1440331 | 0.81 | TP53 (0.70) | TP53LMNAMAPTEPHX2POLB | |
| SCHEMBL1441243 | 0.81 | MAPT (0.52) | TP53LMNAMAPTPTGES | |
| SCHEMBL1440452 | 0.79 | TP53 (0.61) | TP53LMNAMAPTPOLB | |
| SCHEMBL1439972 | 0.79 | SLC6A9 (0.51) | TP53LMNAMAPT | |
| SCHEMBL12811897 | 0.78 | LMNA (0.52) | TP53LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023812-A1 | MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 (MPGES1) INHIBITORS | NOVASAID AB (SE) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011023812-A1 | MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 (MPGES1) INHIBITORS | NOVASAID AB (SE) | 2011-03-03 | — | — | WO | disclosed |