Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969220 | 0.82 | LMNA (0.55) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL5162780 | 0.79 | LMNA (0.59) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL5565405 | 0.75 | CHRM2 (0.59) | CHRM2LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL5644902 | 0.75 | ALDH1A1 (0.64) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL7367629 | 0.73 | LMNA (0.50) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL14476995 | 0.73 | CHRM2 (0.79) | CHRM2LMNAKMT2AMEN1KDM4E | |
| SCHEMBL6994496 | 0.72 | CHRM2 (0.57) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL10282552 | 0.72 | CHRM2 (0.66) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL4477248 | 0.71 | KCNA5 (0.49) | CHRM2LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL7495159 | 0.71 | CHRM2 (0.46) | CHRM2LMNAKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091152-A1 | TRIAZOLOPYRIDINE COMPOUNDS | PFIZER LIMITED (GB) | 2007-08-16 | — | — | WO | disclosed |