Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162780 | 0.85 | LMNA (0.59) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL5969220 | 0.81 | LMNA (0.55) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL4521046 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL7367629 | 0.76 | LMNA (0.50) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL5723909 | 0.76 | HPGD (0.67) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL30646449 | 0.76 | HPGD (0.67) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL10604929 | 0.76 | HPGD (0.67) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL2905172 | 0.75 | KMT2A (0.77) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL14435459 | 0.75 | CHRM2 (0.51) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL2914008 | 0.75 | HPGD (0.65) | ALDH1A1HPGDLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |