Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435498 | 0.78 | GAA (0.46) | SCN9AGAAGRM2MMP3SCN2A | |
| SCHEMBL5408629 | 0.74 | CYP1A1 (0.43) | SCN9AFGFR4GAAGRM2MEN1 | |
| SCHEMBL14524880 | 0.69 | CYP11B2 (0.38) | GRM2MEN1KMT2AMMP3MMP2 | |
| SCHEMBL14524836 | 0.69 | HDAC1 (0.36) | HSD11B1MMP3MMP2 | |
| SCHEMBL303840 | 0.68 | HSD11B1 (0.43) | SCN9AGAAHSD11B1PARP1PARP2 | |
| SCHEMBL20646105 | 0.68 | KDM1A (0.49) | GAAMMP3MMP2CASP1KDM4E | |
| SCHEMBL17179961 | 0.67 | CA2 (0.39) | FGFR4MEN1KMT2A | |
| SCHEMBL28172943 | 0.66 | GRM2 (0.40) | GRM2 | |
| SCHEMBL14525145 | 0.65 | PDE3B (0.37) | GRM2MMP3MMP2 | |
| SCHEMBL14525308 | 0.65 | AR (0.38) | GRM2MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089031-A1 | PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-09 | — | — | WO | disclosed |