Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592172 | 0.79 | RAB9A (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL14943937 | 0.78 | ALDH1A1 (0.54) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14435490 | 0.78 | SCN9A (0.39) | GAASCN9AGRM2SCN2ASCN10A | |
| SCHEMBL1772765 | 0.76 | RAB9A (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1549553 | 0.75 | TRPV3 (0.47) | SCN9A | |
| SCHEMBL3511120 | 0.73 | TKT (0.40) | EGLN2ALDH1A1 | |
| SCHEMBL14524915 | 0.72 | PDCD1 (0.43) | CYP11B2ARMMP3EGLN2ALDH1A1 | |
| SCHEMBL3997043 | 0.72 | MMP3 (0.46) | CYP11B2ARMMP3ALDH1A1CYP2A6 | |
| SCHEMBL14524967 | 0.72 | CYP11B2 (0.40) | CYP11B2ARMMP3ALDH1A1CYP2A6 | |
| SCHEMBL1549232 | 0.72 | TRPV3 (0.47) | GAASCN2ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089031-A1 | PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-09 | — | — | WO | disclosed |