Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437629 | 0.90 | PKM (0.34) | PKMKDM4ETHRBMEN1KMT2A | |
| SCHEMBL11034068 | 0.81 | KDM4E (0.30) | PKMKDM4E | |
| SCHEMBL28125150 | 0.81 | KDM4E (0.30) | PKMKDM4E | |
| SCHEMBL16989821 | 0.79 | PTPN1 (0.30) | — | |
| SCHEMBL221073 | 0.78 | PTPN1 (0.40) | THRBMEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL876236 | 0.78 | MEN1 (0.32) | MEN1CYP1A2KMT2A | |
| SCHEMBL14861290 | 0.78 | CTSK (0.38) | MEN1CYP1A2KMT2AHTT | |
| SCHEMBL19821900 | 0.75 | PKM (0.33) | PKMKDM4ETHRBHTT | |
| SCHEMBL8580311 | 0.74 | PKM (0.32) | PKM | |
| SCHEMBL6130103 | 0.74 | MEN1 (0.34) | THRBMEN1ALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119455852-A | Reaction kettle for preparing acetamido diethyl malonate by reaction | 湖北江田精密化学股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119698408-A | Process for preparing substituted benzamides | 安道麦马克西姆有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119455852-A | Reaction kettle for preparing acetamido diethyl malonate by reaction | 湖北江田精密化学股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-118086431-B | Method for introducing alpha-hydroxy acids into proteins | 修实生物医药(如东)有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-117623973-A | Resolution method of N-acetyl-4-trifluoromethyl phenylalanine and application thereof | 瑞博(杭州)医药科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-116854609-A | Preparation method of diethyl acetamino malonate | 湖北江田精密化学股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116854609-A | Preparation method of diethyl acetamino malonate | 湖北江田精密化学股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-219291429-U | Reaction kettle for preparing diethyl acetamino malonate through reaction | 湖北江田精密化学股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | SHIVALIK RASAYAN LIMITED (IN) | 2022-05-19 | — | — | US | disclosed |
| US-10842893-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2020-11-24 | — | — | US | disclosed |
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
| US-5332746-A | 8,9-annelated-β-carbolines and 8,9-annelated 3,4-dihydro-β-carbolines | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-07-26 | — | — | US | disclosed |
| US-5238923-A | Treating hypertension, hyperaldosteronism, congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5216161-A | PROCESS FOR PREPARING 2,5-DIAMINO-4,6-DICHLOROPYRIMIDINE | BEECHAM GROUP P.L.C. (GB) | 1993-06-01 | — | — | US | disclosed |
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |
| EP-0399556-A1 | Amino-substituted heterocycles as renin inhibitors | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0347980-A1 | 8,9-Annelated beta-carbolines and 8,9-anelated-3,4-dihydro-beta-carbolines | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-12-27 | — | — | EP | disclosed |
| US-4483853-A | ANTICONVULSANTS | COLLINS JAMES F | 1984-11-20 | — | — | US | disclosed |
| US-4477391-A | Amino acid isomers, their production and their medicinal use | COLLINS JAMES F (GB) | 1984-10-16 | — | — | US | disclosed |
| US-4170654-A | Antihypertensive compositions containing N-heterocyclicalanines and α- | MERCK & CO., INC. (US) | 1979-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | S1PR2, S1PR4, S1PR5 | PKM 365/4885KDM4E 92/4885THRB 2451/4885 |
| US-10842893-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | FECH, SLC40A1, TFRC | PKM 1362/4885KDM4E 3507/4885THRB 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.