Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28125150 | 0.90 | KDM4E (0.30) | PKMKDM4E | |
| SCHEMBL1443640 | 0.90 | PKM (0.32) | PKMKDM4ETHRBHTTMEN1 | |
| SCHEMBL11034068 | 0.86 | KDM4E (0.30) | PKMKDM4E | |
| SCHEMBL19821900 | 0.80 | PKM (0.33) | PKMKDM4ETHRBHTT | |
| SCHEMBL27395268 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL27611908 | 0.77 | PTPN1 (0.38) | KDM4EHTTMEN1MAPTKMT2A | |
| SCHEMBL27631088 | 0.77 | TPSAB1 (0.40) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL809243 | 0.75 | DGAT1 (0.40) | PKMKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9707265 | 0.73 | ELANE (0.32) | KDM4E | |
| SCHEMBL29674742 | 0.72 | DGAT1 (0.39) | PKMKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |