Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.51 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.51 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.51 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555012 | 1.00 | EGFR (0.67) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL94484 | 1.00 | EGFR (0.67) | EGFRMAPTMEN1KMT2APOLB | |
| Resorcinol SCHEMBL1507732 | 0.94 | EGFR (0.59) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL29378452 | 0.86 | EGFR (0.69) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL112101 | 0.86 | EGFR (0.69) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL112102 | 0.86 | EGFR (0.69) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL2440067 | 0.84 | EGFR (0.49) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL2440064 | 0.84 | EGFR (0.49) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL29635269 | 0.84 | EGFR (0.49) | EGFRMAPTMEN1KMT2APOLB | |
| SCHEMBL144370 | 0.84 | EGFR (0.67) | EGFRMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563579-B | Azobenzene-polyarylether nitrile composite material and preparation method thereof | 西南石油大学 | 2023-09-15 | — | — | CN | claimed |
| CN-113563579-A | Azobenzene-poly (arylene ether nitrile) composite material and preparation method thereof | 西南石油大学 | 2021-10-29 | — | — | CN | claimed |
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
| EP-1463513-B1 | STABILIZED BRIVUDINE TOPICAL FORMULATIONS | MENARINI RICERCHE SPA (IT) | 2007-02-21 | — | — | EP | claimed |
| US-20040259835-A1 | Stabilized brivudine topical formulations | MENARINI RICERCHE S.P.A. (IT) | 2004-12-23 | — | — | US | claimed |
| EP-1463513-A1 | STABILIZED BRIVUDINE TOPICAL FORMULATIONS | Menarini Ricerche S.p.A. (IT) | 2004-10-06 | — | — | EP | claimed |
| WO-2003051375-A1 | STABILIZED BRIVUDINE TOPICAL FORMULATIONS | MENARINI RICERCHE S.P.A. (IT) | 2003-06-26 | — | — | WO | claimed |
| CN-113563579-B | Azobenzene-polyarylether nitrile composite material and preparation method thereof | 西南石油大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-116033930-A | Mobile front edge sterilization monitoring device | 3M创新有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-113563579-A | Azobenzene-poly (arylene ether nitrile) composite material and preparation method thereof | 西南石油大学 | 2021-10-29 | — | — | CN | disclosed |
| US-10259946-B1 | Sealing agents, methods of making and uses thereof | James Hardie Technology Limited (IE) | 2019-04-16 | — | — | US | disclosed |
| US-9693937-B2 | Foil applicator | HENKEL AG & CO. KGAA (DE) | 2017-07-04 | — | — | US | disclosed |
| US-9173829-B2 | Compositions for dyeing keratin fibers | HENKEL AG & CO. KGAA (DE) | 2015-11-03 | — | — | US | disclosed |
| US-6558433-B2 | Oxidation hair dye | WELLA AG (DE) | 2003-05-06 | — | — | US | disclosed |
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | Wella GmbH (DE) | 2003-03-06 | — | — | US | disclosed |
| US-20020189031-A1 | Use of salts for improving the absorption qualities of anionic direct dyes | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
| US-6485529-B1 | Agent and method for coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-21 | — | — | US | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-6106579-A | MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT | WELLA AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | KRT18, SCNN1B, DDAH1 | CA12 167/4885CA2 360/4885THRB 3141/4885 |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | ALK, DDC, CBR1 | CA12 3003/4885CA2 1190/4885THRB 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.