Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | VCP | P55072 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439828 | 0.90 | TDP1 (0.40) | TP53MAPTVCPTDP1KMT2A | |
| SCHEMBL6966496 | 0.89 | VCP (0.37) | TP53MAPTVCPTDP1NPC1 | |
| SCHEMBL14439829 | 0.88 | VCP (0.36) | TP53MAPTVCPTDP1RECQL | |
| SCHEMBL14439841 | 0.88 | VCP (0.36) | TP53MAPTVCPTDP1NPC1 | |
| SCHEMBL6965896 | 0.88 | VCP (0.36) | TP53MAPTVCPTDP1RECQL | |
| SCHEMBL6973959 | 0.86 | VCP (0.35) | TP53MAPTVCPTDP1RECQL | |
| SCHEMBL6972409 | 0.86 | VCP (0.35) | TP53MAPTVCPTDP1RECQL | |
| SCHEMBL8109133 | 0.86 | VCP (0.35) | TP53MAPTVCPTDP1SMN1; SMN2 | |
| SCHEMBL14439857 | 0.86 | DHODH (0.39) | TP53MAPTTDP1SMN1; SMN2DHODH | |
| SCHEMBL6957630 | 0.86 | DHODH (0.39) | TP53MAPTTDP1SMN1; SMN2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |