Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109133 | 0.92 | VCP (0.35) | VCPTDP1GRM5DHODHADAMTS5 | |
| SCHEMBL14439828 | 0.92 | TDP1 (0.40) | VCPTDP1DHODHTP53MAPT | |
| SCHEMBL6966496 | 0.91 | VCP (0.37) | VCPTDP1DHODHADAMTS5MMP2 | |
| SCHEMBL14439831 | 0.90 | HDAC1 (0.40) | VCPTDP1GRM5DHODHADAMTS5 | |
| SCHEMBL6973959 | 0.90 | VCP (0.35) | VCPTDP1DHODHADAMTS5MMP2 | |
| SCHEMBL6965896 | 0.90 | VCP (0.36) | VCPTDP1DHODHADAMTS5MMP2 | |
| SCHEMBL14439841 | 0.90 | VCP (0.36) | VCPTDP1DHODHADAMTS5MMP2 | |
| SCHEMBL6961635 | 0.88 | TLR8 (0.36) | VCPTDP1DHODHADAMTS5MMP2 | |
| SCHEMBL6968770 | 0.88 | TDP1 (0.35) | VCPTDP1GRM5ADAMTS5MMP2 | |
| SCHEMBL14439830 | 0.88 | TP53 (0.39) | VCPTDP1DHODHTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |