Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970754 | 0.93 | TDP1 (0.34) | VCPTDP1LMNAAPOBEC3GMEN1 | |
| SCHEMBL6963914 | 0.90 | NPC1 (0.38) | LMNAAPOBEC3GMEN1KMT2AALDH1A1 | |
| SCHEMBL14439828 | 0.89 | TDP1 (0.40) | VCPTDP1KMT2ANPC1RAB9A | |
| SCHEMBL6966496 | 0.88 | VCP (0.37) | VCPTDP1NPC1RAB9AMAPT | |
| SCHEMBL14439829 | 0.87 | VCP (0.36) | VCPTDP1NPC1RAB9AMAPT | |
| SCHEMBL6965896 | 0.87 | VCP (0.36) | VCPTDP1NPC1RAB9AMAPT | |
| SCHEMBL14439841 | 0.87 | VCP (0.36) | VCPTDP1NPC1RAB9AMAPT | |
| SCHEMBL8109133 | 0.85 | VCP (0.35) | VCPTDP1MAPTTP53SMN1; SMN2 | |
| SCHEMBL14439830 | 0.85 | TP53 (0.39) | VCPTDP1MEN1KMT2ANPC1 | |
| SCHEMBL6973959 | 0.85 | VCP (0.35) | VCPTDP1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |