Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 15/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439847 | 0.88 | PLA2G2A (0.40) | PLA2G2AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL14439849 | 0.85 | PLA2G2A (0.41) | PLA2G2AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL14439848 | 0.84 | POLB (0.46) | PLA2G2AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL14439852 | 0.74 | TLR7 (0.35) | — | |
| SCHEMBL14439853 | 0.72 | MEN1 (0.32) | TDP1 | |
| SCHEMBL6961674 | 0.72 | TP53 (0.39) | ALDH1A1SMN1; SMN2 | |
| Acetamide SCHEMBL6972197 | 0.72 | TDP1 (0.41) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL6967638 | 0.71 | TDP1 (0.39) | PLA2G2AALDH1A1TDP1 | |
| SCHEMBL7080037 | 0.71 | POLB (0.37) | PLA2G2AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL8109122 | 0.70 | RECQL (0.47) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |