Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439846 | 0.85 | PLA2G2A (0.48) | PLA2G2AALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL6967638 | 0.85 | TDP1 (0.39) | PLA2G2ATSHRALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7080037 | 0.85 | POLB (0.37) | PLA2G2ATSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6975183 | 0.84 | ENPP2 (0.35) | PLA2G2ATSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6972373 | 0.83 | PIM1 (0.36) | TSHRALDH1A1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL6966621 | 0.83 | TDP1 (0.40) | TDP1L3MBTL1KMT2ARECQLMEN1 | |
| SCHEMBL6962251 | 0.83 | TDP1 (0.38) | PLA2G2ATSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14439827 | 0.82 | TDP1 (0.37) | TSHRALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL7086385 | 0.81 | TLR7 (0.35) | ALDH1A1TDP1L3MBTL1KMT2ALMNA | |
| SCHEMBL14439848 | 0.81 | POLB (0.46) | PLA2G2ATSHRALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |