Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439848 | 0.87 | POLB (0.46) | POLBMEN1KMT2A | |
| SCHEMBL14439853 | 0.85 | MEN1 (0.32) | POLBMEN1KMT2A | |
| SCHEMBL14439846 | 0.74 | PLA2G2A (0.48) | — | |
| SCHEMBL6971451 | 0.73 | HSP90B1 (0.33) | — | |
| SCHEMBL7087537 | 0.72 | TBXA2R (0.31) | — | |
| SCHEMBL14439849 | 0.72 | PLA2G2A (0.41) | POLBMEN1KMT2A | |
| SCHEMBL14439855 | 0.72 | TDP1 (0.33) | — | |
| SCHEMBL6975192 | 0.71 | TDP1 (0.43) | POLBMEN1KMT2A | |
| SCHEMBL7078348 | 0.71 | SMN1; SMN2 (0.36) | TLR7POLBMEN1KMT2A | |
| SCHEMBL6966952 | 0.70 | TDP1 (0.34) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |