Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465357 | 0.83 | HPGD (0.64) | HPGDSLC29A1HDAC1HDAC6NSD3 | |
| SCHEMBL1422156 | 0.82 | NSD3 (0.70) | HPGDSLC29A1HDAC1HDAC6NSD3 | |
| SCHEMBL3642511 | 0.82 | HPGD (0.62) | HPGDSLC29A1HDAC1HDAC6NSD3 | |
| SCHEMBL20774516 | 0.75 | HPGD (0.54) | HPGDSLC29A1HDAC1HDAC6MEN1 | |
| SCHEMBL30552245 | 0.75 | HPGD (0.54) | HPGDSLC29A1HDAC1HDAC6MEN1 | |
| SCHEMBL5452399 | 0.74 | ADORA2A (0.72) | HPGDSLC29A1HDAC1HDAC6ADORA2A | |
| SCHEMBL1313539 | 0.73 | HPGD (0.53) | HPGDSLC29A1HDAC1HDAC6NSD3 | |
| SCHEMBL28950091 | 0.73 | HPGD (0.64) | HPGDSLC29A1HDAC1HDAC6MEN1 | |
| SCHEMBL6950422 | 0.73 | HPGD (0.52) | HPGDSLC29A1HDAC1HDAC6MEN1 | |
| SCHEMBL5471657 | 0.73 | HSP90AA1 (0.54) | HPGDHDAC1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | HPGD 2203/4885SLC29A1 17/4885HDAC1 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.