SCHEMBL1444159

SCHEMBL1444159

CCOC(=O)C(Cl)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ALOX15 P16050 1/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
SOAT1 P35610 1/20 0.46
TRPA1 O75762 1/20 0.42
PIN1 Q13526 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
CAD P27708 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.36
GLO1 Q04760 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7940226 0.90 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL18098644 0.90 MGAM (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28229924 0.88 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
Succinic Acid Diethyl Ester SCHEMBL11510951 0.88 CYP1A2 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL9939069 0.87 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL54869 0.87 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL1444162 0.87 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL20811649 0.86 TSHR (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28694430 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL1597955 0.85 SOAT1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552902-B2 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-02-17 US claimed
CN-119330422-B Sodium ion monocrystalline oxide positive electrode material, battery and vehicle 浙江华宇钠电新能源科技有限公司 2025-04-15 CN claimed
CN-119330422-A Sodium ion monocrystalline oxide positive electrode material, battery and vehicle 浙江华宇钠电新能源科技有限公司 2025-01-21 CN claimed
CN-118253905-A Water-soluble rosin emulsion, and preparation method and application thereof 昆山市诺菲尔电子科技有限公司 2024-06-28 CN claimed
CN-118222769-A Multi-carboxylic acid group high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-21 CN claimed
CN-118186152-A Multifunctional high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-14 CN claimed
CN-115667369-B Composition for optical material 三菱瓦斯化学株式会社 2024-04-05 CN claimed
CN-114773404-B High-carboxyl-content lignin dispersing agent, preparation and application thereof in nano pesticide suspending agent 华南理工大学 2023-06-16 CN claimed
EP-4160279-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-04-05 EP claimed
US-20230100848-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-30 US claimed
CN-113501757-B Preparation and refining method of high-purity diethyl chloropropionate 长沙创新药物工业技术研究院有限公司 2022-12-13 CN claimed
EP-3377470-B1 PROCESS FOR THE SYNTHESIS OF INTERMEDIATES USEFUL FOR PREPARING 1,3,4-TRIAZINE DERIVATIVES FMC CORP (US) 2020-11-11 EP claimed
US-10294196-B2 Process for the synthesis of intermediates useful for preparing 1,3,4-triazine derivatives FMC CORP (US) 2019-05-21 US claimed
US-20180334427-A1 Process for the Synthesis of Intermediates Useful for Preparing 1,3,4-Triazine Derivatives FMC CORP (US) 2018-11-22 US claimed
EP-3377470-A1 PROCESS FOR THE SYNTHESIS OF INTERMEDIATES USEFUL FOR PREPARING 1,3,4-TRIAZINE DERIVATIVES FMC Corporation (US) 2018-09-26 EP claimed
CN-102382244-B Gelation-delayed in-situ polymerized water shutoff gel for high-temperature reservoirs UNIV SOUTHWEST PETROLEUM 2013-02-06 CN claimed
CN-102557937-A Preparation method for diethyl fluoromalonate SHANGHAI SINOFLUORO SCIENT CO 2012-07-11 CN claimed
CN-102382244-A Gelation-delayed in-situ polymerized water shutoff gel for high-temperature reservoirs UNIV SOUTHWEST PETROLEUM 2012-03-21 CN claimed
CN-1028100-C Process for preparing phenoxy-heterocyclic compounds MIDICINE INST CHINESE MEDICAL (CN) 1995-04-05 CN claimed
CN-1051039-A Phenoxy group-heterogeneous ring compound MERRELL DOW PHARMA (US) 1991-05-01 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552902-B2 Composition for optical material PAX2, RPL21, PAXBP1 ALDH1A1 1088/4885LMNA 2535/4885HSD17B10 2400/4885
US-10294196-B2 Process for the synthesis of intermediates useful for preparing 1,3,4-triazine derivatives DAZAP1, TALDO1, GMDS ALDH1A1 395/4885LMNA 3909/4885HSD17B10 1637/4885
US-20180334427-A1 Process for the Synthesis of Intermediates Useful for Preparing 1,3,4-Triazine Derivatives DHPS, CYP4Z1, NISCH ALDH1A1 800/4885LMNA 2871/4885HSD17B10 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.