Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337051 | 1.00 | THRB (0.61) | THRBLMNAKDM4EPOLBTDP1 | |
| SCHEMBL30430712 | 1.00 | THRB (0.61) | THRBLMNAKDM4EPOLBTDP1 | |
| SCHEMBL15861958 | 0.84 | KDM4E (0.63) | THRBLMNAKDM4EL3MBTL1KMT2A | |
| SCHEMBL8012698 | 0.83 | THRB (0.51) | THRBLMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL15866803 | 0.82 | ALDH1A1 (0.54) | THRBLMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL15861961 | 0.81 | KDM4E (0.50) | THRBLMNAKDM4EPOLBTDP1 | |
| SCHEMBL9946340 | 0.79 | L3MBTL1 (0.69) | LMNAKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL9944500 | 0.79 | POLB (0.65) | LMNAPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL15866852 | 0.79 | ALDH1A1 (0.56) | THRBKDM4EL3MBTL1MAPTKMT2A | |
| SCHEMBL15866804 | 0.79 | ALDH1A1 (0.56) | THRBKDM4EL3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286605-B | Method for synthesizing isochromanone compounds based on carbon monoxide gas or carbon monoxide alternative source | 武汉大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115260096-B | Method for synthesizing dihydroisoquinolinones based on carbon monoxide gas or carbon monoxide substitution source | 武汉大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115286605-A | Method for synthesizing isochromanone compounds based on carbon monoxide gas or carbon monoxide substitute source | 武汉大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-115260096-A | Method for synthesizing dihydroisoquinolinone compound based on carbon monoxide gas or carbon monoxide alternative source | 武汉大学 | 2022-11-01 | — | — | CN | disclosed |
| US-5936048-A | Method for preparing modified resins and their applications | MITSUI CHEMICALS, INC. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0698620-B1 | Method for preparing modified resins and their applications | MITSUI CHEMICALS INC (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5792814-A | REACTING A RESIN WITH A 5-((4,6-DIAMINO-S-TRIAZIN-2-YL)-NORBORN-2-ENE AND REACTING WITH AN EPOXIDE; FIREPROOFING; MOLDING MATERIALS | MITSUI CHEMICALS, INC. (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5674947-A | HEATING RESIN WITH FUNCTIONALIZED NORBORNENE COMPOUND IN ABSENCE OF REACTION CATALYST OR INITIATOR | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0698620-A1 | Method for preparing modified resins and their applications | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-4176220-A | COORDINATION CATALYST | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1979-11-27 | — | — | US | disclosed |
| US-4068063-A | Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1978-01-10 | — | — | US | disclosed |