SCHEMBL14452879

SCHEMBL14452879

c1cnc2c(c1)-c1ccoc1C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2C P28335 1/20 0.33
▸ TDP1 Q9NUW8 2/20 0.31
▸ TDP2 O95551 1/20 0.31
▸ NSD2 O96028 1/20 0.31
▸ ABL1 P00519 1/20 0.31
▸ PLCG1 P19174 1/20 0.31
▸ CES1 P23141 1/20 0.31
▸ PAX8 Q06710 1/20 0.31
▸ RIN1 Q13671 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ BLM P54132 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ HSP90AA1 P07900 2/20 0.31
▸ HPGD P15428 1/20 0.31
▸ CYP19A1 P11511 2/20 0.31
▸ TBXAS1 P24557 2/20 0.31
▸ CCR1 P32246 3/20 0.30
▸ CCR8 P51685 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585349 0.77 TDP1 (0.42) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL14452884 0.73 MEN1 (0.34) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL27174135 0.68 METAP2 (0.46) HTR2CCES1HPGDKDM4ELMNA
SCHEMBL29360004 0.68 METAP2 (0.46) HTR2CCES1HPGDKDM4ELMNA
SCHEMBL30011414 0.68 METAP2 (0.46) HTR2CCES1HPGDKDM4ELMNA
SCHEMBL9673347 0.68 MAOA (0.41) TDP1TDP2CES1MEN1KMT2A
SCHEMBL51294 0.68 METAP2 (0.46) HTR2CCES1HPGDKDM4ELMNA
SCHEMBL22579802 0.68 TDP1 (0.42) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL10253865 0.66 TDP1 (0.37) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL25983066 0.66 CCR1 (0.43) KMT2AGAACCR1CCR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180138413-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-17 — — US disclosed
US-9966532-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-08 — — US disclosed
US-20140231775-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-21 — — US disclosed
US-8728631-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-20 — — US disclosed
US-20070154732-A1 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138413-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME DCUN1D4, DCUN1D1, FLOT1 HTR2C 3646/4885TDP1 683/4885TDP2 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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