SCHEMBL14452884

SCHEMBL14452884

c1cnc2c(c1)-c1occc1C2

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ PTPRC P08575 2/20 0.32
▸ TDP2 O95551 1/20 0.31
▸ NSD2 O96028 1/20 0.31
▸ ABL1 P00519 1/20 0.31
▸ PLCG1 P19174 1/20 0.31
▸ CES1 P23141 1/20 0.31
▸ PAX8 Q06710 1/20 0.31
▸ RIN1 Q13671 1/20 0.31
▸ GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14452879 0.73 HTR2C (0.33) MEN1THRBBLMKMT2ATDP1
SCHEMBL585349 0.71 TDP1 (0.42) MEN1THRBBLMKMT2ATDP1
SCHEMBL27174135 0.71 METAP2 (0.46) PTPRCCES1
SCHEMBL51294 0.71 METAP2 (0.46) PTPRCCES1
SCHEMBL29360004 0.71 METAP2 (0.46) PTPRCCES1
SCHEMBL30011414 0.71 METAP2 (0.46) PTPRCCES1
SCHEMBL9672535 0.71 MAOA (0.46) MEN1KMT2ATDP1PTPRCTDP2
SCHEMBL9267882 0.69 KMT2A (0.43) MEN1THRBBLMKMT2ATDP1
SCHEMBL7424121 0.67 — —
SCHEMBL25632018 0.66 MAOA (0.32) PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180138413-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-17 — — US disclosed
US-9966532-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-08 — — US disclosed
US-20140231775-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-21 — — US disclosed
US-8728631-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-20 — — US disclosed
US-20070154732-A1 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138413-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME DCUN1D4, DCUN1D1, FLOT1 MEN1 1150/4885THRB 3244/4885BLM 2466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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