Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.62 |
| ▸ | ACLY | P53396 | 2/20 | 0.61 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | WDR5 | P61964 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | S100A9 | P06702 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925257 | 0.76 | METAP2 (1.00) | METAP2ACLYKDM1ASLC10A2SLC10A1 | |
| SCHEMBL21999849 | 0.76 | ACLY (1.00) | ACLYPFKFB3 | |
| SCHEMBL7589357 | 0.75 | S100A9 (0.57) | ACLYPFKFB3TDP1CYP2C9S100A9 | |
| SCHEMBL9996819 | 0.73 | PFKFB3 (1.00) | ACLYPFKFB3TDP1MEN1KMT2A | |
| SCHEMBL7593518 | 0.73 | ACLY (0.61) | ACLYPFKFB3TDP1CYP2C9S100A9 | |
| SCHEMBL3982242 | 0.73 | METAP2 (0.61) | METAP2ACLYTDP1 | |
| SCHEMBL3985574 | 0.72 | METAP2 (0.60) | METAP2PFKFB3MEN1KMT2AKDM1A | |
| SCHEMBL5597963 | 0.72 | CCKBR (0.62) | METAP2ACLYMEN1KMT2AWDR5 | |
| SCHEMBL3988109 | 0.72 | METAP2 (0.62) | METAP2ACLYPFKFB3TDP1MEN1 | |
| SCHEMBL219601 | 0.72 | ALDH1A1 (0.71) | METAP2TDP1MEN1KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | METAP2 915/4885ACLY 713/4885PFKFB3 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.