Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601794 | 1.00 | MAPT (0.38) | MAPTL3MBTL1LMNAHPGDTDP1 | |
| SCHEMBL14460697 | 0.89 | L3MBTL1 (0.40) | MAPTL3MBTL1LMNAHPGDTDP1 | |
| SCHEMBL13508969 | 0.87 | MAPT (0.35) | MAPTL3MBTL1LMNAHPGDTDP1 | |
| SCHEMBL29714903 | 0.87 | MEN1 (0.33) | MAPTL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL23092055 | 0.87 | MEN1 (0.33) | MAPTL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL13508888 | 0.85 | MAPT (0.39) | MAPTL3MBTL1LMNAHPGDGAA | |
| SCHEMBL15590688 | 0.83 | LMNA (0.34) | MAPTL3MBTL1LMNAGAAPTPN1 | |
| SCHEMBL15590684 | 0.83 | LMNA (0.34) | MAPTLMNAHPGDGAAPTPN1 | |
| SCHEMBL13045184 | 0.83 | MAPT (0.42) | MAPTL3MBTL1LMNAHPGDTDP1 | |
| SCHEMBL13508890 | 0.83 | THRB (0.41) | MAPTHPGDTDP1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732063-B2 | Lewis base catalysts and methods thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-08-22 | — | — | US | disclosed |
| CN-113423742-B | Bis (arylphenoxide) lewis base catalysts and methods thereof | 埃克森美孚化学专利公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115427464-A | Lewis base catalyst and process therefor | 埃克森美孚化学专利公司 | 2022-12-02 | — | — | CN | disclosed |
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-12-21 | — | — | US | disclosed |
| CN-113423742-A | Bis (arylphenolate) lewis base catalysts and processes thereof | 埃克森美孚化学专利公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20200254431-A1 | BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-08-13 | — | — | US | disclosed |
| EP-1751169-B1 | BRIDGED BI-AROMATIC CATALYSTS, COMPLEXES, AND METHOD OF USING THE SAME | SYMYX SOLUTIONS INC (US) | 2016-04-13 | — | — | EP | disclosed |
| US-7241714-B2 | Bridged bi-aromatic catalysts, complexes, and methods of using the same | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241714-B2 | Bridged bi-aromatic catalysts, complexes, and methods of using the same | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | PHKB, TYR, ELL | MAPT 2984/4885L3MBTL1 3000/4885LMNA 3299/4885 |
| US-11732063-B2 | Lewis base catalysts and methods thereof | TEC, ALOX12, ELL | MAPT 4692/4885L3MBTL1 2532/4885LMNA 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.