Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446151 | 0.87 | HPGD (0.54) | HPGDMAPTRAB9ASRD5A2SMN1; SMN2 | |
| SCHEMBL1446152 | 0.85 | MAPK14 (0.39) | HPGDMAPTRAB9ASRD5A2MAPK14 | |
| SCHEMBL565574 | 0.76 | HPGD (0.43) | HPGDMAPTRAB9ASRD5A2MAPK14 | |
| SCHEMBL480674 | 0.76 | KMT2A (0.54) | SRD5A2ALDH1A1ELANEKMT2ATHRA | |
| SCHEMBL3682129 | 0.76 | PLK1 (0.40) | ALDH1A1KMT2ATHRATHRB | |
| SCHEMBL27627345 | 0.74 | ALDH1A1 (0.55) | HPGDMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1446163 | 0.74 | HPGD (0.56) | HPGDMAPTRAB9ASRD5A2SMN1; SMN2 | |
| SCHEMBL9638943 | 0.73 | SRD5A2 (0.57) | HPGDMAPTRAB9ASRD5A2SMN1; SMN2 | |
| SCHEMBL12535868 | 0.73 | IDO1 (0.40) | MAPTSMN1; SMN2ALDH1A1KMT2ATHRA | |
| SCHEMBL17111033 | 0.72 | MAPK14 (0.40) | HPGDMAPTRAB9ASRD5A2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297076-A1 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES | Lamberti SpA (IT) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009135895-A1 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES | LAMBERTI SPA (IT) | 2009-11-12 | — | — | WO | disclosed |