Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446271 | 0.85 | HPGD (0.42) | MAPK14HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL1446151 | 0.82 | HPGD (0.54) | HPGDTSHRHTTSMN1; SMN2MAPT | |
| SCHEMBL6019685 | 0.81 | THRA (0.35) | SMN1; SMN2RAB9ATHRATHRBMEN1 | |
| SCHEMBL11799845 | 0.77 | ALDH1A1 (0.48) | TSHRSMN1; SMN2MAPTSRD5A2THRA | |
| SCHEMBL17111033 | 0.76 | MAPK14 (0.40) | MAPK14HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL19462815 | 0.76 | MAPK14 (0.40) | MAPK14HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL15225781 | 0.72 | RXRA (0.35) | RXRARXRB | |
| SCHEMBL565574 | 0.72 | HPGD (0.43) | MAPK14HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL480674 | 0.71 | KMT2A (0.54) | SRD5A2THRATHRBRXRARXRB | |
| SCHEMBL3682129 | 0.71 | PLK1 (0.40) | THRATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297076-A1 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES | Lamberti SpA (IT) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009135895-A1 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES | LAMBERTI SPA (IT) | 2009-11-12 | — | — | WO | disclosed |